Cell identity: a matter of lineage and neighbours
نویسندگان
چکیده
منابع مشابه
T cell lineage commitment: identity and renunciation.
Precursors undertaking T cell development shed their access to other pathways in a sequential process that begins before entry into the thymus and continues through many cell cycles afterward. This process involves three levels of regulatory change, in which the cells' intrinsic transcriptional regulatory factors, expression of signaling receptors (e.g., Notch1), and expression of distinct homi...
متن کاملT cell lineage commitment: identity and renunciation1
Precursors undertaking T-cell development shed their access to other pathways in a sequential process that begins before entry into the thymus and continues through many cell cycles afterwards. This process involves three levels of regulatory change, in which the cells’ intrinsic transcriptional regulatory factors, expression of signaling receptors like Notch1, and expression of distinct homing...
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این تحقیق در ساختار چهار مرحله ای خود هشت هدف را دنبال کرد: در مرحله اول، تنها هدف طراحی و معتبر سازی پرسشنامه ای بومی بر اساس مدل فرهنگی شش بعدی هافستد (2010) بود. این کار با استفاده از داده های جمع شده از 370 نفر و توسط روش آماری sem انجام شد. مرحله دوم که با استفاده از داده های جمع شده از 170 معلم زبان انگلیسی انجام شد دارای دو هدف بود: هدف اول، بررسی فرسایش کاری معلمان زبان از دید ابعاد فره...
Lkb1 maintains Treg cell lineage identity
Regulatory T (Treg) cells are a distinct T-cell lineage characterized by sustained Foxp3 expression and potent suppressor function, but the upstream dominant factors that preserve Treg lineage-specific features are mostly unknown. Here, we show that Lkb1 maintains Treg cell lineage identity by stabilizing Foxp3 expression and enforcing suppressor function. Upon T-cell receptor (TCR) stimulation...
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This paper aims at testing the existence of yardstick competition by estimating a fully specified votefunction on a panel data set of 104 French local governments from 1989 to 2001. When comparing the performance of their incumbent to the one of their "neighbours", voters might consider their close geographical neighbours but also the nearby cities that are similar according to some socio-econo...
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ژورنال
عنوان ژورنال: New Phytologist
سال: 2016
ISSN: 0028-646X,1469-8137
DOI: 10.1111/nph.13859